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A case of panic disorder precipitated by oxymetazoline withdrawal
The Journal of Clinical Psychiatry
|July 1, 1987
Abstract:
Abrupt withdrawal in a healthy man of oxymetazoline nasal spray precipitated a prolonged panic disorder that required hospitalization with extensive evaluations. The pathophysiology of this syndrome is discussed in light of locus ceruleus neuropharmacology. This may be the first report of such a withdrawal syndrome.