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Predictors of success and puncture site complications in the distal radial approach
Akihiro Ikuta1, Shunsuke Kubo1, Kohei Osakada1
1Department of Cardiovascular Medicine, Kurashiki Central Hospital, 1-11 Miwa, Kurashiki, 710-8602, Japan.
Insights
The distal radial approach (DRA) for coronary procedures has a 90.4% success rate. Ultrasonography guidance improves DRA success and reduces puncture site complications, making it a safer option.
Area of Science:
- Cardiology
- Vascular Access
- Interventional Cardiology
Background:
- The distal radial approach (DRA) is an alternative to traditional radial artery access for coronary angiography (CAG) and percutaneous coronary intervention (PCI).
- Predictors for DRA failure and associated puncture site complications remain unclear, necessitating further investigation.
Purpose of the Study:
- To identify predictors of distal radial approach failure.
- To determine factors associated with puncture site complications during coronary procedures.
- To evaluate the impact of ultrasonography guidance on DRA outcomes.
Main Methods:
- Retrospective analysis of 3610 patients undergoing CAG or PCI via DRA between November 2018 and January 2021.
- Primary endpoint: procedural success. Secondary endpoint: puncture site complications (major/minor bleeding, fistula, pseudoaneurysm, neuropathy).
- Statistical analysis to identify predictors of success and complications.
Main Results:
- The overall DRA success rate was 90.4%, with a 7.7% puncture site complication rate.
- Predictors of DRA failure included low body weight and dual antiplatelet therapy.
- Ultrasonography-guided DRA was associated with higher success rates and fewer complications, particularly previous PCI.
- Low body weight and dual antiplatelet therapy were negative predictors for DRA success without complications.
Conclusions:
- Low body weight and dual antiplatelet therapy predict DRA failure and complications.
- Ultrasonography-guided DRA is associated with improved procedural success and reduced puncture site complications.
- DRA is a viable approach, with ultrasonography guidance enhancing its safety and efficacy in coronary interventions.
Abstract:
The distal radial approach (DRA) has been proposed as an alternative approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI); however, the predictors of DRA failure and puncture site complications are unclear. Among 7153 consecutive patients undergoing CAG or PCI between November 2018 and January 2021, 3610 patients undergoing CAG or PCI with DRA were analyzed. The primary endpoint of this study was the procedural success, and the secondary endpoint of this study was puncture site complications during procedure. Puncture site complications during procedure were defined as a composite of major bleeding, minor bleeding, arteriovenous fistula, pseudoaneurysm, and neuropathy. The DRA success rate and the puncture site complication rate were 90.4% and 7.7%, respectively. The predictors of DRA failure were low body weight and dual antiplatelet therapy; those of DRA success were PCI and ultrasonography-guided DRA; those of puncture site complications during procedure were low body weight, peripheral arterial disease, dual antiplatelet therapy, anticoagulant therapy, and PCI; and that of no puncture site complications were previous PCI and ultrasonography-guided DRA. The negative predictors of DRA success with no puncture site complication during procedure were low body weight and dual antiplatelet therapy. The positive predictor of DRA success with no puncture site complication during procedure was ultrasonography-guided DRA. We identified the predictors of DRA failure and puncture site complications during procedure in patients undergoing CAG and PCI with DRA. Ultrasonography-guided DRA was associated with a high DRA success rate and a low puncture site complication rate in patients undergoing CAG or PCI with DRA.
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