Respiratory Reviews in Asthma 2022

Area of Science:

• Pulmonology
• Allergy and Immunology
• Respiratory Medicine

Background:

• Asthma is a prevalent chronic airway inflammatory disease.
• Key features include variable symptoms, reversible obstruction, and bronchospasm.
• Understanding asthma requires continuous review of emerging research.

Purpose of the Study:

• To review significant clinical asthma studies published between March 2021 and February 2022.
• To synthesize findings on comorbidities, diagnostics, therapeutics, and pandemic-related impacts.
• To provide an updated overview of the asthma research landscape.

Main Methods:

• Literature review of clinical studies on asthma.
• Focus on publications from March 2021 to February 2022.
• Inclusion of studies on comorbidities, diagnostics, treatments, and COVID-19.

Main Results:

• Studies explored asthma's relationship with chronic rhinosinusitis, bronchiectasis, and hormone replacement therapy.
• Fractional exhaled nitric oxide (FeNO) utility in predicting severe exacerbations was examined.
• Research on inhaler efficacy, severe asthma control, and new biologic therapies (Phase 2/3) was presented.
• The impact of coronavirus disease 2019 (COVID-19) on asthma patients' prevalence and mortality was investigated.

Conclusions:

• Recent research expands understanding of asthma comorbidities and diagnostic tools like FeNO.
• Advancements in inhaler technology and novel biologic treatments offer new therapeutic avenues.
• The ongoing COVID-19 pandemic necessitates continued research into its effects on asthma patients.