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Updated: Sep 1, 2025

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
2-Amino-4-ferrocenyl-thia-zole
Bertin Anzaldo1, Pankaj Sharma1, Claudia P Villamizar1
1Instituto de Química, Circuito Exterior Cd. Universitaria, PO Box 04510, Ciudad de México, Mexico.
Abstract:
The title compound, [Fe(C5H5)(C8H7N2S)], was synthesized by the direct reaction of acetyl-ferrocene, thio-urea and resublimed iodine. The structure shows one mol-ecule in the asymmetric unit. The amino-thia-zole ring makes an angle of 14.53 (13)° with the ferrocenyl ring to which it is attached. In the crystal, pairs of complex mol-ecules inter-act via inter-molecular N-H⋯N hydrogen bonds, forming a cyclic dimer which then inter-acts with other dimers through C-H⋯π inter-actions.
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