Hepatosplenic T Cell Lymphoma: Diagnostic Conundrum
Zachariah Chowdhury1, Yookarin Khonglah2, Vandana Raphael2
1Department of Pathology, Homi Bhabha Cancer Hospital/MPMMCC (TATA Memorial Hospital), Varanasi, Uttar Pradesh, India.
Summary
Hepatosplenic T cell lymphoma (HSTCL) is a rare, aggressive cancer. This case highlights diagnostic challenges and emphasizes the need for high suspicion in immunocompetent individuals presenting with related symptoms.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Hepatosplenic T cell lymphoma (HSTCL) is an aggressive, rare peripheral T cell lymphoma, often associated with immunosuppression.
- It characteristically involves extranodal sites like the liver, spleen, and bone marrow with sinusoidal infiltration.
