NeuroCOVID-19: a critical review

Area of Science:

• Neurology
• Infectious Diseases
• Public Health

Background:

• The COVID-19 pandemic significantly impacted neurology services, with an influx of patients presenting acute neurological syndromes.
• While acute SARS-CoV-2 neurological complications are better understood, persistent neurological symptoms (Long COVID) represent a growing and complex challenge.

Purpose of the Study:

• To review neurological manifestations of acute SARS-CoV-2 infection.
• To examine the phenomenon of Long COVID and the role of patient communities in medical knowledge production.

Main Methods:

• This study employed a narrative review methodology.
• Data synthesis on neurological complications associated with SARS-CoV-2 infection and Long COVID.

Main Results:

• Acute SARS-CoV-2 infection is linked to encephalopathy, cerebrovascular disease, headache, and peripheral nervous system issues.
• Long COVID is a dynamic concept co-defined by patients, physicians, and scientists, highlighting the collaborative nature of medical understanding.

Conclusions:

• The co-production of knowledge in Long COVID signifies a shift towards patient-led research and activism.
• This patient-involved approach brings patient suffering to the forefront but may present challenges in maintaining methodological rigor.