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Updated: Sep 1, 2025

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Polymeric Microneedle Array Fabrication by Photolithography
Published on: November 17, 2015
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3D-printed microneedle arrays for drug delivery
Rong Li1, Li Zhang1, Xuebing Jiang1
1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Summary
3D printing enables the fabrication of complex microneedle arrays for minimally invasive transdermal drug delivery. This technology accelerates the clinical translation of microneedle arrays, advancing medical applications.
Area of Science:
- Biomedical Engineering
- Materials Science
Background:
- Microneedle arrays offer efficient, minimally invasive transdermal drug delivery.
- Fabricating microneedle arrays is challenging due to their small size and intricate structures.
Purpose of the Study:
- To review the current state of 3D printing for microneedle array fabrication.
- To discuss the advantages of 3D printing for microneedle arrays and their clinical translation.
Main Methods:
- Review of existing literature on 3D printing technologies applied to microneedle array fabrication.
- Analysis of the benefits and challenges associated with 3D-printed microneedle arrays for drug delivery.
Main Results:
- 3D printing is a powerful technology for creating complex, personalized microneedle arrays.
- 3D printing facilitates the advancement and clinical translation of microneedle array technology.
Conclusions:
- 3D printing significantly enhances microneedle array manufacturing.
- This review provides an overview of 3D-printed microneedle arrays for drug delivery applications.

