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Updated: Sep 1, 2025

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
Published on: September 13, 2020
Neurogenic Thoracic Outlet Syndrome—Presentation, Diagnosis, and Treatment.
Nora F Dengler1, Maria T Pedro, Thomas Kretschmer
1Department of Neurosurgery, Charité-Universitätsmedizin Berlin; District Hospital of Günzburg, Neurosurgical Department of the University of Ulm; Department of Neurosurgery and Neurorestauration, Klinikum Klagenfurt Am Wörthersee, Klagenfurt, Austria; Peripheral Nerve Unit Nord, Christliches Krankenhaus Quakenbrück GmbH, Quakenbrück; Department of Neurosurgery, Helios Klinikum Erfurt.
Neurogenic thoracic outlet syndrome (nTOS) is common, but treatment research is limited. Physiotherapy shows some benefit, while surgery offers significant improvement for many patients with nTOS.
Area of Science:
- Medical research
- Clinical neurology
- Surgical outcomes
Background:
- Thoracic outlet syndrome (TOS) involves neurovascular compression at the chest-neck transition.
- Neurogenic TOS (nTOS) presents with sensorimotor symptoms in the upper extremities, often movement-related.
- nTOS is the most prevalent form of TOS, with estimated incidence and prevalence rates.
Purpose of the Study:
- To outline the clinical presentation patterns of nTOS.
- To provide an overview of diagnostic approaches for nTOS.
- To review current treatment strategies for nTOS.
Main Methods:
- A selective literature search was conducted.
- Included studies comprised prospective observational studies and randomized controlled trials (RCTs).
- Systematic reviews and meta-analyses were also considered.
Main Results:
- No multicenter RCTs exist for nTOS treatment.
- Physiotherapy demonstrates positive effects in 27-59% of cases.
- Surgery yields significant benefits in 56-90% of patients after conservative treatment failure, with supraclavicular decompression showing variable outcomes.
Conclusions:
- Treatment studies for nTOS are limited in quality and quantity.
- Surgical management approaches vary widely based on surgeon and patient factors.
- Standardized classification and comparative studies are needed for better interpretation of nTOS treatment outcomes.
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