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Updated: Sep 1, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Embolic Cerebrovascular Accident Secondary to Device-Related Thrombus Post WATCHMAN Device Implantation
Palak Patel1, Nagapratap Ganta1, Giuseppe Filice1
1Internal Medicine, Hackensack Meridian Health Ocean University Medical Center, Brick, USA.
Insights
Device-related thrombus (DRT) can form after Watchman implantation for atrial fibrillation (AF) management. This case highlights a DRT leading to a cerebrovascular accident (stroke), emphasizing potential risks of left atrial appendage closure devices.
Area of Science:
- Cardiology
- Medical Devices
- Thrombosis
Background:
- Atrial fibrillation (AF) is a common arrhythmia requiring management to prevent thromboembolism.
- Anticoagulation is standard for stroke prevention in AF, but bleeding risks exist.
- Left atrial appendage closure (LAAC) devices like Watchman offer an alternative for stroke risk reduction.
Observation:
- This case report details a patient who developed device-related thrombus (DRT) after Watchman implantation.
- The DRT subsequently led to an embolic cerebrovascular accident (CVA).
Findings:
- Device-related thrombus (DRT) formation is a significant risk associated with LAAC devices.
- Embolic events, such as stroke, can occur secondary to DRT in patients with LAAC devices.
Implications:
- This case underscores the importance of monitoring for DRT after LAAC procedures.
- Further research into mitigating DRT formation and its complications is warranted.
- Careful patient selection and risk-benefit assessment are crucial when considering LAAC devices.
Abstract:
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias encountered. Aggressive and appropriate management, along with identification and modification of risk factors, remains at the forefront of evidence-based practice. Thrombus formation (primarily in the left atrial appendage) and consequent thromboembolism are risks associated with AF. Anticoagulation is utilized to prevent and reduce AF-induced complications such as stroke, heart failure, and death. However, in instances when the risk of bleeding from anticoagulation outweighs the benefits of stroke prevention, other modalities such as left atrial appendage closure (LAAC) devices like the WATCHMAN device (Boston Scientific, MA) are utilized. LAAC devices, such as the WATCHMAN device, are also not without significant risks, one of them being device-related thrombus (DRT) formation. We present a case of device-related thrombus formation post WATCHMAN implantation and a subsequent embolic cerebrovascular accident (CVA).
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