Related Experiment Video
Updated: Sep 1, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
A Comprehensive Nursing Model Combined with High-Quality Nursing Intervention for Antiviral Therapy in Patients with
Wei Yang1, Xiaofeng Tian1, Jing Liang2
1Department of Hepatobiliary and Pancreatic Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Objective:
To investigate the effect of comprehensive nursing combined with high-quality nursing intervention on the compliance, anxiety, and mental state of patients with chronic hepatitis B undergoing antiviral therapy.
Methods:
A total of 100 patients with chronic hepatitis B admitted to China-Japan Union Hospital from December 2017 to August 2020 were recruited and assigned to receive either routine nursing (control group, n = 50) or comprehensive nursing plus high-quality nursing (observation group, n = 50) via the random number table method. The outcome measures included compliance, psychological state, and treatment effects.
Results:
Before the nursing, there was no significant difference in the compliance scores between the two groups of patients (P > 0.05). After the nursing, the observation group had higher compliance scores than the control group (P < 0.001). Before the intervention, the two groups had similar Self-Rating Anxiety Scale (SAS) scores (P > 0.05). After the intervention, patients in the observation group showed lower SAS scores and a lower incidence of negative emotions as compared to the control group (P < 0.001). The observation group showed a better outcome in terms of quality of life, Medical Coping Modes Questionnaire (MCMQ) scores, and the General Self-Efficacy Scale (GSES) scores when compared to those of the control group (P < 0.001). A higher treatment effective rate was witnessed in the observation group in contrast to the control group (P < 0.001).
Conclusion:
The comprehensive nursing model combined with high-quality nursing intervention improves the psychological state and compliance of patients with chronic hepatitis B, with favorable treatment efficiency, which shows good potential for clinical promotion.
Related Concept Videos
Chronic Kidney Disease IV: Nursing Management
Chronic Kidney Disease III: Interprofessional Care
Chronic Pancreatitis II: Collaborative Care
Assessment:
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Nephrotic Syndrome III : Nursing Management
Myocarditis IV: Nursing Management

