Related Experiment Video
Updated: Sep 1, 2025
10:46
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
18.9K
First interobserver agreement of optical coherence tomography in the bile duct: A multicenter collaborative study
Amy Tyberg1, Isaac Raijman2, Monica Gaidhane1
1Gastroenterology, Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States.
Endoscopy International Open
|August 18, 2022
Summary
Optical coherence tomography (OCT) shows promise for diagnosing biliary strictures. Interobserver agreement for malignancy diagnosis using OCT was substantial, indicating its potential as a valuable tool.
Area of Science:
- Gastroenterology
- Medical Imaging
Background:
- Optical coherence tomography (OCT) offers subsurface visualization for evaluating indeterminate biliary strictures.
- Preliminary studies suggest OCT has standardized characteristics indicative of malignancy.
Purpose of the Study:
- To assess interobserver agreement in identifying OCT criteria for biliary strictures.
- To evaluate the diagnostic performance of OCT in differentiating malignant from benign biliary strictures.
Main Methods:
- Fourteen endoscopists reviewed an atlas of OCT criteria and 35 de-identified video clips.
- Interobserver agreement was assessed using Intraclass Correlation (ICC) analysis for specific OCT criteria and final diagnosis.
Main Results:
- Excellent interobserver agreement (ICC > 0.7) was observed for several OCT criteria, including dilated hypo-reflective structures and layering effacement.
- Diagnostic ICC for both neoplastic (0.8) and non-neoplastic (0.8) conditions was excellent.
- Overall diagnostic accuracy for malignancy was 51%.
Conclusions:
- Biliary OCT is a promising new modality for evaluating indeterminate biliary strictures.
- Interobserver agreement for malignancy diagnosis using OCT was substantial (ICC=0.8).
- Further studies are required to validate these findings.
