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Concurrent alcoholic cirrhosis and malignant peritoneal mesothelioma in a patient: A case report

Liang Liu1, Xiao-Yan Zhu1, Wen-Jie Zong1

  • 1Department of Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250011, Shandong Province, China.

World Journal of Clinical Cases
|August 18, 2022
PubMed
Abstract

Insights

This case report details a rare instance of malignant peritoneal mesothelioma (MPM) co-occurring with alcoholic cirrhosis. Early diagnosis of MPM is crucial due to its vague symptoms and potential for misdiagnosis.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Malignant peritoneal mesothelioma (MPM) is a rare cancer originating in the abdominal cavity.
  • MPM diagnosis is challenging due to nonspecific symptoms, often mimicking liver diseases like alcoholic cirrhosis.

Observation:

  • A 63-year-old male with a history of heavy alcohol consumption presented with persistent abdominal distension.
  • Initial treatment for presumed alcoholic cirrhosis was ineffective, prompting further investigation.

Findings:

  • Exploratory laparotomy revealed epithelioid malignant peritoneal mesothelioma.
  • Pathological examination confirmed MPM coexisting with alcoholic cirrhosis, a previously unreported combination.

Implications:

  • This case highlights the importance of considering MPM in patients with vague abdominal symptoms, especially those with risk factors for liver disease.
  • Timely and accurate diagnosis of MPM is essential for effective treatment and improved patient outcomes.
Keywords:
Abdominal distensionAscitesCase reportCirrhosisComputed tomographyMalignant peritoneal mesothelioma

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