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Penile metastasis from rectal carcinoma: A case report
Jun-Jie Sun1, Shi-Yu Zhang1, Jun-Jie Tian1
1Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 311000, Zhejiang Province, China.
World Journal of Clinical Cases
|August 18, 2022
Summary
Penile metastasis from rectal carcinoma (PMRC) is rare, with a median survival of 150 days. Early detection and multimodal treatment may improve outcomes for this aggressive cancer.
Area of Science:
- Oncology
- Urology
- Gastroenterology
Background:
- Penile metastasis from rectal carcinoma (PMRC) is an exceptionally rare clinical event.
- PMRC is associated with a poor prognosis, with limited cases reported in medical literature.
Observation:
- A 49-year-old male presented with penile pain during urination, two months post-Dixon operation for rectal carcinoma.
- Imaging revealed a penile nodule, pathologically confirmed as intestinal-type adenocarcinoma.
Findings:
- The median time to metastasis occurrence is approximately 24 months, with a survival time of 150 days post-diagnosis.
- Negative prognostic factors include poor differentiation, lymph node involvement, early metastasis, large nodule size, and treatment abandonment.
Implications:
- Multimodal treatment including surgical resection, chemotherapy, and radiotherapy, alongside close follow-up, may enhance survival outcomes.
- This case highlights the importance of considering rare metastatic patterns in urological and oncological practice.

