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Related Concept Videos

Osmoregulation in Fishes02:32

Osmoregulation in Fishes

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When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?
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Related Experiment Video

Updated: Sep 1, 2025

Paired Patch Clamp Recordings from Motor-neuron and Target Skeletal Muscle in Zebrafish
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Paired Patch Clamp Recordings from Motor-neuron and Target Skeletal Muscle in Zebrafish

Published on: November 20, 2010

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Superfast fish show superfast coupling.

Ben Short

    The Journal of General Physiology
    |August 18, 2022
    PubMed
    Summary

    Zebrafish skeletal muscle fibers exhibit the fastest excitation-contraction coupling kinetics ever recorded in vertebrate locomotion. This JGP study highlights rapid muscle activation in these models.

    Area of Science:

    • Muscle physiology
    • Comparative biology
    • Zebrafish models

    Background:

    • Excitation-contraction coupling (ECC) is fundamental to muscle function.
    • Vertebrate locomotor muscles have varying ECC kinetics.
    • Zebrafish are increasingly used as models for muscle research.

    Discussion:

    • The study measured unprecedentedly fast ECC kinetics in adult zebrafish.
    • These findings suggest unique adaptations in zebrafish muscle.
    • Comparison with other vertebrate models is crucial.

    Key Insights:

    • Adult zebrafish possess the fastest ECC kinetics in vertebrate locomotor muscles.
    • This rapid response has implications for understanding muscle function and evolution.
    • The JGP study provides a new benchmark for muscle activation speed.

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    Related Experiment Videos

    Last Updated: Sep 1, 2025

    Paired Patch Clamp Recordings from Motor-neuron and Target Skeletal Muscle in Zebrafish
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    Published on: November 20, 2010

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    Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish
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    Outlook:

    • Further research can explore the molecular mechanisms behind this rapid ECC.
    • Investigating how these kinetics influence swimming performance is warranted.
    • Zebrafish models may offer novel insights into muscle diseases.