Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.1K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.1K
Pleiotropy01:33

Pleiotropy

40.9K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
40.9K
Organization of Genes02:07

Organization of Genes

69.1K
Overview
69.1K
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

1.3K
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
1.3K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

10.0K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
10.0K
piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

7.0K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Children's Urgent Reduction of Forearm Fractures in the Emergency Department (CURFFED) project : a national prospective trainee-led collaborative audit of practice.

Bone & joint open·2026
Same author

Study of South Asian genomes illuminates roots of milk drinking.

Science (New York, N.Y.)·2026
Same author

Did lead poisoning help drive human evolution?

Science (New York, N.Y.)·2025
Same author

Denisovans, Neanderthals gave Indigenous Americans key mucus gene.

Science (New York, N.Y.)·2025
Same author

Quantification and dosimetric impact of intra-fractional bladder changes during CBCT-guided online adaptive radiotherapy for pelvic cancer treatments.

Journal of applied clinical medical physics·2025
Same author

Practical Approach to Computed Tomography Guided Online Adaptive Radiation Therapy for Abdominopelvic Tumors.

Practical radiation oncology·2025

Related Experiment Video

Updated: Sep 1, 2025

Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs
05:47

Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs

Published on: March 3, 2023

1.4K

Scientists isolate the genes that shape the human pelvis.

Michael Price

    Science (New York, N.Y.)
    |August 18, 2022
    PubMed
    Summary

    Embryonic pelvic development reveals the origins of bipedal locomotion. This study uncovers how the human pelvis shape, essential for walking upright, forms during early development.

    Area of Science:

    • Evolutionary biology
    • Developmental biology
    • Human anatomy

    Background:

    • The human pelvis exhibits a unique shape optimized for bipedalism, distinguishing it from other primates.
    • Understanding the developmental processes that shape the embryonic pelvis is crucial for insights into human evolution.

    Discussion:

    • This research investigates the embryonic origins of the human pelvis, focusing on the developmental mechanisms that establish its bipedal-primed morphology.
    • Analysis of embryonic tissue samples provides a window into the early stages of pelvic structural development.

    Key Insights:

    • The study identifies key developmental events and genetic factors influencing the embryonic formation of the human pelvis.
    • Findings elucidate how the pelvis acquires its characteristic shape conducive to upright walking during embryonic development.

    More Related Videos

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
    07:06

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

    Published on: April 3, 2017

    47.0K
    A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
    08:22

    A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

    Published on: December 1, 2017

    8.7K

    Related Experiment Videos

    Last Updated: Sep 1, 2025

    Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs
    05:47

    Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs

    Published on: March 3, 2023

    1.4K
    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
    07:06

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

    Published on: April 3, 2017

    47.0K
    A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
    08:22

    A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

    Published on: December 1, 2017

    8.7K

    Outlook:

    • Further research can explore the genetic and molecular pathways governing human pelvic evolution.
    • This work provides a foundation for understanding congenital pelvic abnormalities and their developmental basis.