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Updated: Aug 31, 2025

Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
[Mitochondrial aspects of fatigue in sports]
A A Khadartsev1, N A Fudin2, V A Badtieva3
1Medical Institute of the Tula State University, Tula, Russia.
Abstract:
National literature on fatigue in sports related to mitochondrial activity and possible drug and non-drug correction approaches over the past 5 years was reviewed. The significance of acidosis as a factor limiting muscle activity, energy production, adenosine triphosphate utilization, and activation of lipid peroxidation was shown. The results of ultrastructure studies in the modulation of gene expression related to the characteristics of tonic and phasic muscles and a histochemical method of assessing the types of these muscle fibers are presented. Options of overtraining prevention in sports by drug and non-drug methods are evaluated.
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