[Clinical Role of M Protein in Multiple Myeloma and Lymphoma --Review]
Liu-Yun Zhang1, Yun-Hui Xiang1, Yan-Ying Li1
1School of Medicine University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, China.
Abstract:
M protein is often expressed in multiple myeloma and also can be detected in several lymphoma such as Waldenstrm macroglobulinaemia. M protein level can reflect the malignant degree and even genetic abnormality of multiple myeloma and lymphoma to some extent to predict the progress of the diseases, and the therapeutic response and prognosis of the disease can be evaluated by monitoring the M protein level and its change degree. This article reviews the role of M protein in the progression and prognosis of multiple myeloma and lymphoma, and discusses the differences in M protein expression between multiple myeloma and lymphoma, in order to provide new insights for clinical diagnosis, monitoring and evaluation of therapeutic effect.
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