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Related Experiment Videos

The 14 & 6-associated clinical complex: a rejected hypothesis revisited.

G R DeLong, P B Rosenberger, S Hildreth

    Journal of Child Neurology
    |April 1, 1987
    PubMed
    Summary

    The 14 & 6 Hz positive spike phenomenon on electroencephalograms (EEGs) is linked to behavioral disorders and aggression in children. This finding suggests clinical associations warranting further investigation.

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    Area of Science:

    • Neurophysiology
    • Child Neurology
    • Behavioral Science

    Background:

    • The 14 & 6 Hz positive spike phenomenon on electroencephalograms (EEGs) is often classified as a normal variant.
    • Previous understanding suggested limited clinical significance for this EEG pattern.

    Purpose of the Study:

    • To re-evaluate the clinical significance of the 14 & 6 Hz positive spike phenomenon.
    • To investigate potential correlations between this EEG finding and behavioral or neurological issues in children.

    Main Methods:

    • Comparative analysis of EEG findings in children with and without the 14 & 6 Hz pattern.
    • Correlation of EEG results with clinical data, including behavioral assessments and neurological evaluations.
    • Detailed symptom tabulation in children with prominent 14 & 6 Hz spikes.

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    Main Results:

    • In children referred for sleep EEGs, the 14 & 6 Hz pattern correlated with behavior disorder and aggression.
    • Among children with behavioral problems, 52% exhibited the 14 & 6 Hz pattern (excluding those with other paroxysmal EEG findings).
    • Symptomatic children with prominent 14 & 6 Hz spikes presented a complex clinical picture involving temper, mood, attention, learning, and sleep disturbances.

    Conclusions:

    • The 14 & 6 Hz positive spike phenomenon is associated with specific clinical symptoms and behavioral disorders in children.
    • This EEG finding warrants further study due to its demonstrated clinical associations.
    • Re-evaluation suggests the 14 & 6 Hz pattern may not be merely a normal variant but could indicate underlying issues.