The most critically injured polytrauma patient mortality: should it be a measurement of trauma system performance?

Benjamin Maurice Hardy1,2, Natalie Enninghorst2, Kate Louise King1,2

  • 1Department of Traumatology, John Hunter Hospital and University of Newcastle, Newcastle, NSW, 2310, Australia.

Insights

Trauma mortality has decreased, but not for critical polytrauma patients (ISS 50-75). This high-risk group requires further study to improve survival rates in severe injury cases.

Area of Science:

  • Trauma surgery
  • Public health
  • Injury epidemiology

Background:

  • Developed trauma systems have achieved record low mortality rates for major trauma (Injury Severity Score [ISS] > 15).
  • However, critical polytrauma patients (ISS 50-75) represent a subgroup with persistently high mortality risks.
  • This study investigates whether overall trauma mortality improvements are driven by reduced moderate injuries, while critical polytrauma outcomes remain unchanged.

Purpose of the Study:

  • To test the hypothesis that reductions in trauma mortality are primarily due to improvements in moderate injury severity.
  • To determine if mortality rates for critical polytrauma patients (ISS 50-75) have remained persistently high despite overall system improvements.
  • To analyze trends in trauma mortality over a 20-year period in a Level-1 trauma center.

Main Methods:

  • A 20-year retrospective analysis (ending December 2021) of a Level-1 trauma center registry.
  • Inclusion criteria: all trauma patients with an Injury Severity Score (ISS) > 15.
  • Multivariate logistic regression analysis was used to examine mortality trends for the entire cohort and the critical polytrauma subset (ISS 50-75).

Main Results:

  • A total of 8462 severely injured patients (ISS > 15) were analyzed.
  • Critical polytrauma patients (ISS 50-75) constituted 2.8% (n=238) of the severely injured cohort.
  • Overall mortality for ISS > 15 decreased from 11.3% to 9.4% (Adjusted OR 0.98).
  • Mortality for critical polytrauma patients (ISS 50-75) showed no significant change, remaining between 46.2% and 60.0% (Adjusted OR 0.96).

Conclusions:

  • Improvements in trauma mortality over the past two decades have not benefited all patient groups equally.
  • Mortality rates for critical polytrauma patients (ISS 50-75) remain high and have not significantly improved.
  • The critical polytrauma group (ISS 50-75) is a well-defined cohort suitable for targeted research and reporting to drive improvements in care and outcomes.
Abstract