Actin remodeling driven by circLIMA1: sperm cell as an intriguing cellular model.

Francesco Manfrevola1, Nicoletta Potenza2, Teresa Chioccarelli1

  • 1Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Summary

Endocannabinoids regulate sperm quality by controlling circular RNA (circRNA) cargo. CB1 receptor knockout mice show altered circRNA profiles, impacting sperm maturation and nuclear actin remodeling.

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