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Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

36
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
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Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

22
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

21
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
21
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

35
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
35
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

25
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
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Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Related Experiment Video

Updated: Aug 31, 2025

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models
09:01

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models

Published on: January 27, 2023

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A giant vesical calculus.

Gopalakrishnan Chandrasekaran1, Chelian Mathirajan1, Rajasabai Pandiarajan1

  • 1Department of Urology and Anesthesiology, Nithilaa Nursing Home, Madurai, Tamil Nadu, India.

Indian Journal of Urology : IJU : Journal of the Urological Society of India
|August 19, 2022
PubMed
Summary

Giant bladder stones (vesical calculi) over 100g are rare. This case study details a 1334g calculus, highlighting potential factors like limited medical access contributing to extreme growth.

Area of Science:

  • Urology
  • Nephrology
  • Medical Case Reports

Background:

  • Vesical calculi (bladder stones) are a common urological condition.
  • Giant vesical calculi exceeding 100g are exceptionally rare in clinical practice.

Purpose of the Study:

  • To report a rare case of a giant vesical calculus.
  • To discuss potential predisposing factors for extreme calculus formation.

Main Methods:

  • Case report of a patient presenting with a large vesical calculus.
  • Clinical evaluation and documentation of calculus weight and patient history.

Main Results:

  • A single giant vesical calculus weighing approximately 1334g was identified.
  • The patient presented with surprisingly mild symptoms despite the calculus size.

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Conclusions:

  • Extreme enlargement of vesical calculi may occur due to factors such as limited access to healthcare.
  • Mild symptoms can mask the presence of significantly large bladder stones, emphasizing the need for thorough diagnosis.