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Updated: Aug 31, 2025
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Mixed Metal Allergy Ancillary to Surgical Staples
Naveed E Ahmed1, Rio Varghese2, Ameen Abdel-Khalek1
1Medicine, Saint James School of Medicine, Park Ridge, USA.
Cureus
|August 19, 2022
Abstract:
Metal allergies to surgical clips are atypical and often neglected as a differential. It becomes even more unexpected when there is a lack of relevant medical history of the patient reacting poorly to known metals. This study entails the unique finding of newly discovered hypersensitivity to nickel and zirconium, metals commonly found in surgical clips, in a 28-year-old female who underwent laparoscopic cholecystectomy with a cholangiogram.
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