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Published on: May 21, 2019
Selective C(sp2)-H bond functionalization of olefins via visible-light-induced photoredox-quinuclidine dual catalysis
Xin-Tao Gu1, Long-Hai Li1, Yin Wei1
1State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Lu, Shanghai, 200032, China. weiyin@sioc.ac.cn.
Abstract:
The site selective C(sp2)-H bond functionalization of olefins has been achieved through a visible-light-induced photoredox-quinuclidine dual catalysis upon merging the quinuclidinium radical cation addition to alkene strategy and the distal heteroaryl ipso-migration strategy. This synthetic protocol features a simple operation with readily available starting materials in good step-economy to access alkenylheteroaromatic products in moderate to good yields under mild conditions. A plausible cascade catalytic reaction mechanism is also proposed.
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