Two new terpenoid glycosides from Isodon macrocalyx
Related Experiment Video
Updated: Aug 31, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Xiaoqin Liang1, Yanling Chang1, Xinlan Guan2
1State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin, China.
Abstract:
One previously undescribed tricyclo-diterpenoid saponin (1), one undescribed dammarane triterpenoid saponin (2) and four known triterpenoids (3-6) were isolated from the aerial part of Isodon macrocalyx. Their structures were determined using 1 D- and 2 D-NMR, HRESIMS, and comparison of their spectroscopic data with previously reported data. The isolates were evaluated for their anti-HBV activity in vitro using the HBV transfected Hep G2.2.15 cell line. Compounds 2 and 3 exhibited moderate anti-HBV activity.
Related Concept Videos
Drugs that Stabilize Microtubules
Biosynthesis of Polysaccharides
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.

