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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Adult Stem Cells01:33

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Updated: Aug 31, 2025

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Pride in STEM worldwide.

Juno Obedin-Maliver, Erinma Ochu, Franklin Zhong

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    |August 19, 2022
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    Summary
    This summary is machine-generated.

    LGBTQ+ scientists share how their identity impacts their experiences in Science, Technology, Engineering, and Mathematics (STEM). Six researchers discuss how their expertise, focus, institutions, and location influence their scientific journeys, promoting inclusivity.

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    Area of Science:

    • Science, Technology, Engineering, and Mathematics (STEM) fields.

    Background:

    • LGBTQ+ scientists face unique challenges and experiences within STEM.
    • Understanding these experiences is crucial for fostering inclusivity.

    Purpose of the Study:

    • To explore how LGBTQ+ identity shapes scientists' experiences in STEM.
    • To highlight diverse perspectives from researchers globally.

    Main Methods:

    • Qualitative data collection through interviews or personal accounts.
    • Focus on individual narratives of six LGBTQ+ scientists.

    Main Results:

    • Experiences are influenced by a combination of personal identity, scientific discipline, institutional environment, and geographic location.
    • Each scientist's journey is unique, shaped by intersecting factors.

    Conclusions:

    • Diverse factors shape the experiences of LGBTQ+ scientists in STEM.
    • Sharing these perspectives is vital for advancing inclusivity in scientific communities.