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Bystander LECT2 amyloidosis in tumor nephrectomy
A J Gallan1, B Bhasin-Chhabra2, D Kilari3
1Department of Pathology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI, 53226, USA. agallan@mcw.edu.
CEN Case Reports
|August 19, 2022
Summary
Pathologic examination of kidney tissue unexpectedly revealed leukocyte chemotactic factor 2 (LECT2) amyloidosis in a Punjabi patient undergoing treatment for renal cell carcinoma. This finding expands awareness of LECT2 amyloidosis beyond its typical demographic.
Area of Science:
- Nephrology
- Pathology
- Oncology
Background:
- Pathologic evaluation of non-neoplastic renal parenchyma in nephrectomy specimens is crucial for identifying systemic and renal pathologies.
- Renal cell carcinoma treatment often involves nephrectomy, providing opportunities for incidental findings in surrounding kidney tissue.

