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Related Experiment Video

Updated: Aug 31, 2025

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Published on: April 29, 2014

Bystander LECT2 amyloidosis in tumor nephrectomy.

A J Gallan¹, B Bhasin-Chhabra², D Kilari³

¹Department of Pathology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI, 53226, USA. agallan@mcw.edu.

CEN Case Reports

|August 19, 2022

Summary

Pathologic examination of kidney tissue unexpectedly revealed leukocyte chemotactic factor 2 (LECT2) amyloidosis in a Punjabi patient undergoing treatment for renal cell carcinoma. This finding expands awareness of LECT2 amyloidosis beyond its typical demographic.

Area of Science:

Nephrology
Pathology
Oncology

Background:

Pathologic evaluation of non-neoplastic renal parenchyma in nephrectomy specimens is crucial for identifying systemic and renal pathologies.

Keywords:

Amyloidosis LECT2 Nephrectomy Onconephrology Punjabi Renal cell carcinoma Renal pathology

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Renal cell carcinoma treatment often involves nephrectomy, providing opportunities for incidental findings in surrounding kidney tissue.