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Published on: December 11, 2017
Institutional case volume and mortality after aortic and mitral valve replacement: a nationwide study in two Korean
Karam Nam1, Eun Jin Jang2, Jun Woo Jo3
1Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Insights
Higher heart valve surgery volume is linked to better patient survival. This study found lower mortality rates in high-volume centers for aortic valve replacement (AVR) and mitral valve replacement (MVR).
Area of Science:
- Cardiovascular Surgery
- Health Services Research
- Outcomes Research
Background:
- Limited research exists on the volume-outcome relationship in heart valve surgery.
- This study investigates the association between hospital case volume and mortality for aortic valve replacement (AVR) and mitral valve replacement (MVR).
Purpose of the Study:
- To determine if higher institutional case volumes correlate with lower in-hospital mortality rates after AVR and MVR.
- To inform discussions on centralizing cardiac valve replacement procedures.
Main Methods:
- Analysis of a Korean healthcare insurance database (2009-2016) for adult AVR and MVR cases.
- Hospitals categorized into low, medium, and high volume based on annual case numbers for AVR and MVR.
- Comparison of in-hospital mortality rates across different volume groups.
Main Results:
- Higher in-hospital mortality observed in low- and medium-volume centers for both AVR and MVR compared to high-volume centers.
- Adjusted risk of mortality was significantly higher in lower-volume centers for both procedures.
- AVR: Low-volume (8.3%), Medium-volume (4.0%), High-volume (2.6%). MVR: Low-volume (9.3%), Medium-volume (6.3%), High-volume (2.9%).
Conclusions:
- Lower institutional case volume is associated with increased in-hospital mortality after AVR and MVR.
- Findings suggest potential benefits of regionalizing or centralizing cardiac valve replacement surgeries.
- Optimizing patient outcomes may be achieved through strategic centralization of these procedures.
Background:
There are only a handful of published studies regarding the volume-outcome relationship in heart valve surgery. We evaluated the association between institutional case volume and mortality after aortic valve replacement (AVR) and mitral valve replacement (MVR).
Methods:
Two separate cohorts of all adults who underwent AVR or MVR, respectively, between 2009 and 2016 were analyzed using a Korean healthcare insurance database. Hospitals performing AVRs were divided into three groups according to the average annual case volume: the low- (< 20 cases/year), medium- (20-70 cases/year), and high-volume centers (> 70 cases/year). Hospitals performing MVRs were also grouped as the low- (< 15 cases/year), medium- (15-40 cases/year), or high-volume centers (> 40 cases/year). In-hospital mortality after AVR or MVR were compared among the groups.
Results:
In total, 7875 AVR and 5084 MVR cases were analyzed. In-hospital mortality after AVR was 8.3% (192/2318), 4.0% (84/2102), and 2.6% (90/3455) in the low-, medium-, and high-volume centers, respectively. The adjusted risk was higher in the low- (OR 2.31, 95% CI 1.73-3.09) and medium-volume centers (OR 1.53, 95% CI 1.09-2.15) compared to the high-volume centers. In-hospital mortality after MVR was 9.3% (155/1663), 6.3% (94/1501), and 2.9% (56/1920) in the low-, medium-, and high-volume centers, respectively. Compared to the high-volume centers, the medium- (OR 1.97, 95% CI 1.35-2.88) and low-volume centers (OR 2.29, 95% CI 1.60-3.27) showed higher adjusted risk of in-hospital mortality.
Conclusions:
Lower case volume is associated with increased in-hospital mortality after AVR and MVR. The results warrant a comprehensive discussion regarding regionalization/centralization of cardiac valve replacements to optimize patient outcomes.
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