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Related Experiment Video

Updated: Aug 31, 2025

Generation of a Human iPSC-Based Blood-Brain Barrier Chip

Generation of a Human iPSC-Based Blood-Brain Barrier Chip

Published on: March 2, 2020

Towards establishing human body-on-a-chip systems.

Zhong Alan Li¹, Rocky S Tuan²

¹Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

Stem Cell Research & Therapy

|August 20, 2022

Summary

A novel body-on-a-chip (BoC) system links multiple organs-on-chips (OoCs) to mimic tissue interactions. Future work aims to boost BoC physiological relevance and scalability for disease research and personalized medicine.

Area of Science:

Biotechnology
Tissue Engineering
Physiological Modeling

Background:

Body-on-a-chip (BoC) platforms integrate multiple organs-on-chips (OoCs) to model inter-tissue communication.
Recent advancements include a BoC system with four fluidically connected OoCs.

Keywords:

Body-on-a-chip Disease modelling Drug testing Microfluidic device Organ-on-a-chip Patient-on-a-chip Precision medicine Stem cell

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