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Serum electrolyte abnormalities in pediatric patients presenting to an emergency department with various diseases:
Chen-Wei Yen1, Mei-Ching Yu2, Jung Lee1
1Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Insights
Serum electrolyte abnormalities (SEAs) affect 0.14% of pediatric emergency department visits. Hyponatremia is common in young children, while hypokalemia affects older children, impacting intensive care unit stays.
Area of Science:
- Pediatric Emergency Medicine
- Clinical Chemistry
- Pediatric Critical Care
Background:
- Serum electrolyte abnormalities (SEAs) are common in pediatric patients.
- Understanding the prevalence and patterns of SEAs is crucial for effective management in emergency settings.
Purpose of the Study:
- To evaluate the prevalence and frequency of SEAs in children presenting to a pediatric emergency department (PED).
- To assess age-related differences in SEAs and their associated clinical conditions.
Main Methods:
- Retrospective observational study of pediatric patients (≤18 years) with electrolyte panels from a PED.
- Data collected over a 5-year period (January 1, 2016, to August 31, 2021).
- Patients categorized into three age groups: <4 years, 4-11 years, and 12-18 years.
Main Results:
- A total of 250 (0.14%) out of 182,058 pediatric patients had SEAs.
- Hyponatremia was the most frequent SEA in children <4 years old.
- Hypokalemia was the most common SEA in children aged 4-18 years.
- SEAs were associated with gastrointestinal, renal, and endocrine diseases.
- Younger children (<4 years) experienced longer pediatric intensive care unit (PICU) stays.
Conclusions:
- The overall detection rate of SEAs in the PED was 0.14%.
- Age-specific patterns of SEAs were observed: hyponatremia in younger children and hypokalemia in older children.
- SEAs in infants and young children correlated with extended PICU admissions.
Background:
This study evaluated the prevalence and frequency of serum electrolyte abnormalities (SEAs) in children presenting to a pediatric emergency department (PED) with various diseases.
Methods:
Pediatric patients (≤18 years) with blood electrolyte panels obtained in the PED of Lin-Kou Chang Gung Memorial Hospital, Taiwan, in the 5 years from January 1, 2016, to August 31, 2021, were enrolled in this retrospective observational study. Patients were divided into three age groups: Group A, < 4 years; Group B, 4-11 years; and Group C, 12-18 years. The associations between SEAs and clinical diseases in children and age-related differences were assessed.
Results:
This study included 182,058 pediatric patients visiting our PED over a 5-year period. A total of 250 (0.14%) patients with SEAs were included in the analysis. The study population consisted of 127 boys and 123 girls with a median (IQR) age of 9.0 (3.2-14.1) years. Hospital admission was required in 86.4% (n = 216) of the patients, and 32.4% (n = 81) of them were admitted to the pediatric intensive care unit (PICU). The median (IQR) hospital stay and PICU stay was 6.5 (4.0-11.0) and 4.0 (3.0-8.0) days, respectively. The PICU stay was longer in Group A (p < 0.05) and shorter in group C (p < 0.05). Hyponatremia was the most common SEA in group A (46.3%, n = 31), while hypokalemia was common in groups B (54.2%, n = 52) and C (32.2%, n = 28). Gastrointestinal, renal, and endocrine diseases were common clinical conditions associated with SEAs in pediatric patients in our PED.
Conclusion:
The detection rate of SEAs in patients in the PED was 0.14%. Hyponatremia was a common SEA in pediatric patients aged <4 years, while the most common electrolyte disorder in those >4 years old was hypokalemia. In infants and young children, SEAs were associated with a longer PICU stay.
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