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Updated: Aug 31, 2025

Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
Bloodstream infection by Rhodococcus corynebacterioides in a pediatric patient diagnosed with high-risk
Ana Rosa Méndez-Cruz1, Georgina Elizabeth Félix-Bermúdez1, Dinora Virginia Aguilar-Escobar1
1Hospital Infantil Teletón de Oncología, Querétaro, Mexico.
Abstract:
Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.

