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Updated: Aug 5, 2026
Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Utility of thromboelastogram in cardiac surgery in Jacobsen syndrome associated with platelet dysfunction: a case
Chikashi Takeda1, Akiko Hirotsu1, Gento Yasuhara1
1Department of Anesthesia, Kyoto University Hospital, Kyoto, 606-8507, Japan.
Background:
Jacobsen syndrome is a rare genetic disorder with multiple congenital anomalies and platelet abnormalities caused by chromosome 11 deletion.
Case Presentation:
A 7-month-old boy with thrombocytopenia underwent ventricular septal defect closure. At the beginning of surgery, the platelet count was 168 × 103/μL, and heparinized kaolin with heparinase reaction time (HKH-R), which represents clot formation time, was prolonged at 30.4 min. Platelet transfusion was continued, and at the end of surgery, the platelet count and HKH-R values improved to 215 × 103/μL and 15 min, respectively.
Conclusions:
As anesthetic management of patients with abnormal platelet function, the viscoelasticity test might be useful in evaluating hemostatic capacity.
