Related Experiment Video
Updated: Feb 15, 2026
08:25
Evaluating the Function of the Foot Core System in the Elderly
Published on: March 11, 2022
3.3K
Naproxen tolerability in the elderly: a summary report.
The Journal of Rheumatology
|April 1, 1987
Summary
Elderly patients tolerated naproxen well in clinical trials. Older adults (65+) showed no increased risk of side effects or toxicity compared to younger individuals.
Area of Science:
- Pharmacology
- Geriatric Medicine
- Clinical Trials
Background:
- Naproxen is a common nonsteroidal anti-inflammatory drug (NSAID) used for pain and inflammation.
- Assessing drug tolerability in elderly populations is crucial due to physiological changes associated with aging.
Purpose of the Study:
- To evaluate the tolerability and safety profile of naproxen in elderly patients.
- To compare naproxen's side effect profile in patients aged 65 and older versus younger patients.
Main Methods:
- Analysis of data from 9 double-blind clinical trials involving patients with rheumatoid arthritis or osteoarthritis.
- Assessment of patient withdrawal rates due to complaints.
- Monitoring of reported patient complaints and clinically significant laboratory abnormalities.
Main Results:
- Elderly patients (26% of 1,178 participants, aged 65+) did not show a decreased tolerability of naproxen.
- No consistent increase in naproxen toxicity was observed in the elderly group compared to younger patients.
- Rates of withdrawal, reported complaints, and laboratory abnormalities were comparable between age groups.
Conclusions:
- Naproxen demonstrates acceptable tolerability and safety in elderly patients with rheumatoid arthritis or osteoarthritis.
- Age (65 and older) does not appear to be a significant factor in naproxen's adverse event profile.
- Findings support the continued use of naproxen in geriatric populations when indicated.
More Related Videos
08:22Remotely Supervised Transcranial Direct Current Stimulation: An Update on Safety and Tolerability
Published on: October 7, 2017
8.6K
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
13.3K
Related Concept Videos
01:045-Number Summary
5.8K
In a dataset, the 5-number summary includes the minimum data value, the data value of the first quartile, the median data value or data value of the second quartile, the data value of the third quartile, and the maximum data value. These 5 data values can be visualized as a box and whisker plot.
In a box plot, the minimum and maximum data values represent the lower and upper whiskers in the graph, and the median is designated as the center of the box in the chart. The first quartile and third...
In a box plot, the minimum and maximum data values represent the lower and upper whiskers in the graph, and the median is designated as the center of the box in the chart. The first quartile and third...
5.8K
01:31Discharge Summary Forms
1.3K
The discharge summary is crucial as it enables a smooth transition from a healthcare facility to a patient's home or another care setting. This critical document facilitates seamless continuity of care, ensuring patients receive the necessary support and attention.
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
1.3K
01:24Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
01:25Types of Reports I: Hands-off Report
1.6K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.6K
01:21Types of Reports II: Incident or Occurrence Report
1.3K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
01:26Types of Reports III: Telephone and Verbal Reports
1.0K
Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
Here's an overview of each type:
Telephone Orders
1.0K