Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

3.0K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.0K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.7K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.7K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

343
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
343
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

666
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
666
Hormones Regulating Blood Glucose01:16

Hormones Regulating Blood Glucose

3.8K
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A CTC-Based Speech Recognition Network Fusing Local Convolution and Global Attention.

Sensors (Basel, Switzerland)·2026
Same author

Computer Vision-Guided Automated External Defibrillator System Improves Cardiopulmonary Resuscitation Accuracy: A Randomized Crossover Trial.

Health science reports·2026
Same author

A Progressive Feature Learning Network for <i>Cordyceps sinensis</i> Image Recognition.

Sensors (Basel, Switzerland)·2025
Same author

Blood Glucose Prediction Method Based on Particle Swarm Optimization and Model Fusion.

Diagnostics (Basel, Switzerland)·2022
Same author

Prediction of Particulate Concentration Based on Correlation Analysis and a Bi-GRU Model.

International journal of environmental research and public health·2022
Same author

Tensor Multi-Clustering Parallel Intelligent Computing Method Based on Tensor Chain Decomposition.

Computational intelligence and neuroscience·2022
Same journal

RETRACTION: miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.

Disease markers·2026
Same journal

RETRACTION: Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice.

Disease markers·2026
Same journal

RETRACTION: Kartogenin Induced Adipose-Derived Stem Cell Exosomes Enhance the Chondrogenic Differentiation Ability of Adipose-Derived Stem Cells.

Disease markers·2026
Same journal

Correction to "KIF20A Affects the Prognosis of Bladder Cancer by Promoting the Proliferation and Metastasis of Bladder Cancer Cells".

Disease markers·2026
Same journal

RETRACTION: Antiresistin Neutralizing Antibody Alleviates Doxorubicin-Induced Cardiac Injury in Mice.

Disease markers·2026
Same journal

RETRACTION: Expression of miR-155 in Serum Exosomes in Children with Epilepsy and Its Diagnostic Value.

Disease markers·2025
See all related articles

Related Experiment Video

Updated: Aug 31, 2025

Deep Neural Networks for Image-Based Dietary Assessment
13:19

Deep Neural Networks for Image-Based Dietary Assessment

Published on: March 13, 2021

9.3K

A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction.

He Xu1,2,3,4,5, Qunli Zheng1, Jingshu Zhu1

  • 1School of Computer Science, Nanjing University of Posts and Telecommunications, Nanjing 210023, China.

Disease Markers
|August 22, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces a novel deep learning model integrating medical knowledge for disease prediction. The model achieves high accuracy in diabetes prediction, aiding early detection and diagnosis.

More Related Videos

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K
Author Spotlight: Advancing Alzheimer's Research &#8211; Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.2K

Related Experiment Videos

Last Updated: Aug 31, 2025

Deep Neural Networks for Image-Based Dietary Assessment
13:19

Deep Neural Networks for Image-Based Dietary Assessment

Published on: March 13, 2021

9.3K
A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K
Author Spotlight: Advancing Alzheimer's Research &#8211; Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.2K

Area of Science:

  • Medical Informatics
  • Artificial Intelligence in Medicine
  • Computational Biology

Background:

  • Deep learning models show promise in disease prediction but lack interpretability and clinical integration.
  • Integrating medical expertise is crucial for enhancing the clinical applicability of AI in healthcare.

Purpose of the Study:

  • To develop a disease prediction model combining knowledge representation learning and deep learning.
  • To improve the interpretability and clinical utility of deep learning for disease prediction.

Main Methods:

  • Constructing a relationship graph of physical indicators and test values based on normal ranges.
  • Encoding human physical examination data using knowledge representation learning.
  • Inputting patient data vectors into a deep learning model with self-attention and CNN for prediction.

Main Results:

  • The model achieved 97.18% accuracy and 87.55% recall in diabetes prediction.
  • Outperformed traditional machine learning methods like Lasso, Ridge, SVM, Random Forest, and XGBoost.
  • Demonstrated a 5.34% increase in recall compared to the best-performing Random Forest model.

Conclusions:

  • Integrating medical knowledge into deep learning via knowledge representation learning enhances disease prediction.
  • The proposed model shows significant potential for early diabetes detection and diagnostic assistance.
  • This approach offers a pathway to more interpretable and clinically relevant AI in medicine.