Related Experiment Video
Updated: Aug 31, 2025

06:02
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
153
Modified transapical-transcatheter aortic valve implantation
Dritan Useini1,2, Justus Strauch1
1Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany.
Journal of Clinical and Translational Research
|August 22, 2022
Summary
Transcatheter aortic valve implantation (TAVI) can be challenging for patients with severe arterial disease. A modified transapical TAVI technique offers a safe, artery-sparing alternative when traditional approaches are impossible.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- High-grade aortic stenosis necessitates intervention, with transcatheter aortic valve implantation (TAVI) and surgery as primary options.
- Patients with extensive arterial disease and calcification present significant challenges for standard TAVI approaches.
- Comorbidities like porcelain aorta, Leriche syndrome, and prior vascular interventions further limit arterial access options.
Purpose of the Study:
- To present a modified transapical TAVI technique for patients unsuitable for transvascular TAVI due to severe panarteriopathy.
- To evaluate the safety and efficacy of the artery-no-touch transapical TAVI approach in a select patient cohort.
Main Methods:
- Modification of the standard transapical TAVI procedure to ensure an artery-no-touch technique.
- Application of the modified technique in patients with end-stage peripheral artery disease and no viable arterial access.
- Retrospective analysis of procedural outcomes and in-hospital complications.
Main Results:
- The modified artery-no-touch transapical TAVI was successfully employed in six patients.
- No procedural or in-hospital complications were observed in the treated patient group.
- This technique provides a viable solution for complex TAVI candidates with limited arterial access.
Conclusions:
- The modified artery-no-touch transapical TAVI is a safe and effective alternative for patients with severe arterial disease who cannot undergo conventional TAVI.
- This approach expands treatment options for high-risk aortic stenosis patients with challenging vascular anatomy.
- Further research may explore broader application and long-term outcomes of this modified TAVI technique.

