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Related Concept Videos

Necrosis01:16

Necrosis

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Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
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Related Experiment Video

Updated: Aug 31, 2025

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
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Acute necrotizing encephalopathy.

Roberto Hernandez1, Richi Ota1, Yasier Medina1

  • 1Department of Neurology, Texas Tech University Health Sciences Center , Lubbock , Texas.

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|August 22, 2022
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Summary
This summary is machine-generated.

This case report details a rare adult case of acute necrotizing encephalopathy (ANE) following influenza B infection. Despite aggressive treatment, the patient succumbed, highlighting ANE

Keywords:
acute necrotizing encephalitisinfluenza Bneurological complications

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Viral Encephalopathies

Background:

  • Influenza virus infections can rarely lead to severe neurological complications.
  • Acute necrotizing encephalopathy (ANE) is a rare but often fatal neurological complication associated with influenza.
  • Literature on ANE specifically linked to influenza B virus in adults is scarce.

Observation:

  • A previously healthy 29-year-old male presented with influenza B virus infection.
  • He experienced a sudden and severe decline in mental status.
  • Brain MRI revealed multifocal lesions characteristic of ANE, with negative cerebrospinal fluid studies.

Findings:

  • The patient exhibited clinical and imaging findings consistent with ANE secondary to influenza B.
  • Cerebrospinal fluid analysis did not identify an infectious agent.
  • The patient's condition deteriorated rapidly, leading to death despite comprehensive medical interventions.

Implications:

  • This case underscores the potential severity of influenza B virus infection in adults, leading to ANE.
  • It highlights the limited understanding and treatment options for ANE in the adult population.
  • Further research is needed to elucidate the pathogenesis and improve outcomes for adult ANE cases.