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Updated: Aug 31, 2025
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Pyomyositis presenting as myonecrosis secondary to methicillin-resistant Staphylococcus aureus bacteremia in chronic
Shannon Coombs1,2, Albert Bui2, Haares S Mirzan2
1Mayo Clinic Alix School of Medicine, Jacksonville, Florida.
Abstract:
The incidence of pyomyositis in immunocompromised patients with HIV, diabetes, myelodysplastic syndromes, and acute lymphocytic leukemia is well documented. However, there are only a few reports of pyomyositis and myonecrosis in patients with chronic lymphocytic leukemia (CLL). We present a rare case of pyomyositis presenting as myonecrosis secondary to methicillin-resistant Staphylococcus aureus bacteremia in a 72-year-old patient with CLL. Pyomyositis, although rare, warrants increased provider awareness and management, especially among CLL patients who pose diagnostic and treatment challenges.
Insights
Pyomyositis, a serious bacterial muscle infection, is rare in chronic lymphocytic leukemia (CLL) patients. This case highlights methicillin-resistant Staphylococcus aureus bacteremia leading to pyomyositis and myonecrosis in a CLL patient.
Area of Science:
- Infectious Diseases
- Hematology
- Oncology
Background:
- Pyomyositis incidence is documented in various immunocompromised states.
- Reports of pyomyositis and myonecrosis in chronic lymphocytic leukemia (CLL) are scarce.
Observation:
- A 72-year-old patient with CLL developed pyomyositis.
- The condition presented as myonecrosis secondary to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia.
Findings:
- This case represents a rare occurrence of pyomyositis with myonecrosis in a patient with CLL.
- MRSA bacteremia was identified as the causative agent.
Implications:
- Increased provider awareness for pyomyositis is crucial, particularly in immunocompromised patients.
- CLL patients present unique diagnostic and management challenges for pyomyositis.
- Early recognition and treatment of MRSA bacteremia can prevent severe outcomes like myonecrosis.
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