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Updated: Aug 31, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Apparent reversal of early ischemic changes on non-contrast computed tomography following successful endovascular
Shail Thanki1, Karl A Kasischke2, Maxim Mokin1
1Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida 33629.
Abstract:
Early ischemic changes seen on Non-contrast computed tomography (NCCT) secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion (CTP) may overpredict the infarct core in patients with large vessel occlusion (LVO) presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of "ghost infarct core" which is the mismatch in the infarct core as seen on follow-up imaging. We present a case which potentially supports the concept of "ghost infarct core" evaluated not only by CTP but also NCCT in a patient with LVO following successful thrombectomy.

