Related Experiment Video
Updated: Aug 31, 2025

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
Published on: May 18, 2018
COVID-19-Related Intestinal Ischemia in A 7-Year Old Boy
Balázs Fadgyas1, Gábor István Garai1, János Schnur2
1Department of Surgery and Traumatology, Heim Pál National Institute of Paediatrics, Budapest, Hungary.
Insights
Pediatric multisystem inflammatory syndrome (PIMS) can cause severe abdominal issues. This case highlights COVID-19-related intestinal ischemia and Meckel's diverticulitis requiring surgical intervention.
Area of Science:
- Pediatric surgery
- Infectious diseases
- Pediatric critical care
Background:
- Pediatric multisystem inflammatory syndrome (PIMS) often presents with severe abdominal pain and vomiting.
- Early pandemic reports focused on medical management for suspected surgical abdomen in PIMS, discouraging surgical exploration.
- Limited data exists on COVID-19-associated surgical complications like intestinal ischemia in children.
Observation:
- A non-immunocompromised child with PIMS presented with symptoms suggestive of acute surgical abdomen.
- The child developed intestinal ischemia complicated by Meckel's diverticulitis.
- Surgical intervention was deemed necessary despite initial hesitations due to COVID-19 concerns.
Findings:
- This case demonstrates a severe outcome of COVID-19-related vasculitis contributing to intestinal ischemia and Meckel's diverticulitis in a child.
- Vasculitis and hypotension episodes likely played a role in the ischemic event.
- Surgical intervention was successfully performed, indicating its potential necessity in select PIMS cases.
Implications:
- Highlights the need for careful surgical evaluation in children with PIMS presenting with abdominal emergencies.
- Suggests that COVID-19-related vasculitis can lead to severe gastrointestinal complications requiring surgical management.
- Emphasizes that a proactive surgical approach may be critical for specific PIMS-associated abdominal conditions.
Abstract:
Severe abdominal pain and vomiting are common symptoms in children with pediatric multisystem inflammatory syndrome (PIMS). Mesenteric lymphadenitis and aseptic peritonitis are predominantly reported in cases where acute surgical abdomen was suspected and laparotomy was performed at the early stage of the pandemic. These reports generally discouraged surgeons to perform exploration in COVID-19-related cases and medical management was prioritized. Only a few COVID-19-specific surgical cases with intestinal ischemia were published. Here, we report another case of COVID-19-related intestinal ischemia complicated with Meckel's diverticulitis in a non-immunocompromised child who clearly required surgical intervention. In our case, the combination of COVID-19-related vasculitis and low blood pressure episodes may have contributed to this severe outcome.
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...

