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Updated: Aug 31, 2025

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Published on: April 13, 2017

Microglia orchestrate neuroinflammation.

Ricardo A Feldman¹

¹Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.

|August 22, 2022

Summary

This summary is machine-generated.

Microglia, immune cells in the brain, are key players in the neurological damage seen in neuropathic Gaucher disease. These findings highlight microglia's role in disease progression.

Area of Science:

Neuroscience
Immunology
Genetics

Background:

Gaucher disease is a lysosomal storage disorder.
Neuropathic forms of Gaucher disease involve significant neurological complications.

Keywords:

Gaucher disease Gba1 NK cells human lipids medicine microglia mouse neuroinflammation

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The precise mechanisms driving neurological damage are not fully understood.