Right ventricular obstruction in various types of hypertrophic cardiomyopathy

Area of Science:

• Cardiology
• Genetics
• Internal Medicine

Background:

• Hypertrophic cardiomyopathy (HCM) is a genetically transmitted cardiac disease.
• HCM presents with diverse clinical and hemodynamic features, including obstructive and non-obstructive patterns.
• Common forms include asymmetric septal hypertrophy (ASH) and apical hypertrophy (AH).

Observation:

• Right ventricular hypertrophic obstruction (RVHO) is an uncommon HCM variant, typically co-occurring with left ventricular HCM.
• This report presents one case of RVHO with IHSS (inletскага ventricular outflow tract obstruction).
• Two cases with midventricular obstruction (MO) and one case of RVHO with AH were also described.

Findings:

• The study highlights the occurrence of RVHO in conjunction with various left ventricular HCM subtypes.
• It documents a rare case of RVHO combined with apical hypertrophy (AH).
• The findings expand the understanding of HCM's varied presentations.

Implications:

• These findings contribute to the clinical spectrum of hypertrophic cardiomyopathy.
• Understanding these rare presentations is crucial for accurate diagnosis and management.
• Further research into the genetic and hemodynamic factors of these variants is warranted.