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Updated: Aug 11, 2026

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
[Detection of thrombotic vascular lesions by MR tomography]
Abstract:
Magnetic resonance tomography (MRT) was used to investigate 54 patients with a variety of vascular lesions; 38 of those had essential hypertension, including malignant arterial hypertension in 9. Sixteen patients had vascular arterial hypertension, with thrombosis-complicated vascular lesions: unilateral renal artery thrombosis was detected in 6, aortic aneurysm with perimural thrombosis, in 5, Leriche's syndrome, in 3, and unilateral iliac artery thrombosis, in 2. Twenty seven normal subjects, investigated by radionuclide angiography, were taken as controls. Hypertensive patients showed aortic convolution, thickened aortic wall and a certain irregularity of signals inside the aortic lumen, an evidence of possible perimural thrombosis as well as turbulent currents. These data coincided with ultrasonic, computerized tomographic and angiographic findings. In patients with unilateral renal arterial thrombosis, an area of prostenotic dilatation or the thrombosed renal artery itself could be clearly seen. In patients with Leriche's syndrome, thrombosed iliac artery was better visualized because of a greater vascular diameter. In patients with aortic aneurysm, aneurysmal bag, with impulses of different intensity inside the lumen and blurred outline, could be clearly seen. It is concluded that MRT can be used for the diagnosis of vascular thrombotic lesions.
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