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Bilateral Cryptophthalmus: First Case Report from Nepal.

Nayana Pant1, Subash Bhatta, Gulshan Bahadur Shrestha

  • 1Geta Eye Hospital, Dhangadhi, Nepal.

Nepalese Journal of Ophthalmology : a Biannual Peer-Reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH
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Summary

Cryptophthalmos, a rare genetic disorder causing eye casing, presents management challenges. Surgical reconstruction offers cosmetic improvement but rarely restores useful vision in Fraser syndrome cases.

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Area of Science:

  • Ophthalmology
  • Genetics
  • Pediatric Surgery

Background:

  • Cryptophthalmos involves partial or complete skin casing of the eyeball.
  • It is frequently associated with systemic abnormalities, forming Fraser syndrome.
  • This rare genetic disorder has limited documented cases and complex management.

Observation:

  • A neonate presented with orbital swelling and a deformed eye.
  • Examination revealed a skin-covered right orbit and left eye abnormalities including superior symblepharon.
  • Associated findings included bilateral ear deformities and right renal agenesis.

Findings:

  • Surgical intervention involved globe and cyst removal on the right.
  • Left eye surgery included upper eyelid reconstruction and symblepharon release with amniotic membrane transplantation.
  • This case highlights the challenges in managing cryptophthalmos and Fraser syndrome.

Implications:

  • Reconstructive surgery can improve cosmetic outcomes for cryptophthalmos.
  • Achieving useful vision post-surgery remains a significant challenge.
  • This report is the first from Nepal concerning cryptophthalmos management.