Related Experiment Video
Updated: Aug 31, 2025
11:48
Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
Published on: April 4, 2019
16.1K
Population-based hospitalization burden estimates for respiratory viruses, 2015-2019
Richard K Zimmerman1, G K Balasubramani2, Helen E A D'Agostino2
1Department of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Influenza and Other Respiratory Viruses
|August 23, 2022
Summary
Non-influenza respiratory viruses cause significant hospitalizations in adults. Rhinovirus/enterovirus and RSV contribute substantially to the burden, highlighting the need for broader public health strategies beyond influenza prevention.
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- Acute respiratory infections (ARIs) lead to millions of illnesses and hundreds of thousands of hospitalizations annually in the US.
- Key viruses responsible for ARIs include influenza, parainfluenza, human metapneumovirus, coronaviruses, respiratory syncytial virus (RSV), and human rhinoviruses.
Purpose of the Study:
- To estimate the population-based hospitalization burden of various respiratory viruses (RVs) in adults aged 18 years and older.
- To analyze RV hospitalization data over a four-year period (July 1, 2015, to June 30, 2019) in Allegheny County, Pennsylvania.
Main Methods:
- Utilized population-based statewide hospital discharge data.
- Incorporated health system electronic medical record (EMR) data for RV testing.
- Employed census data and a published methodology to calculate the hospitalization burden.
Main Results:
- Rhinovirus/enterovirus, influenza A, and RSV were the most frequently detected viruses.
- Annual hospitalization burden per 100,000 population varied: rhinovirus/enterovirus (137-174), influenza A (99-182), and RSV (56-81).
- Hospitalization burden increased with age, with different patterns for rhinovirus/enterovirus and influenza A in adults under and over 65 years.
Conclusions:
- Significant hospitalization burden is attributed to non-influenza respiratory viruses.
- These findings are crucial for informing research priorities and guiding public health policy for ARI prevention and management.
Related Concept Videos
01:51Vaccinations
45.2K
Overview
45.2K
01:31Common Respiratory Disorders
852
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
852
01:30Pneumonia I: Introduction
311
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
311
01:28Pneumonia IV: Management
434
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
434
01:22Respiratory Volumes and Capacities
2.5K
The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
2.5K
01:30Pneumonia V: Nursing management and Prevention
2.4K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.4K