Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

360
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
360
Understanding Sleep01:11

Understanding Sleep

467
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
467
Management of Insomnia01:19

Management of Insomnia

314
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
314
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

1.5K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.5K
Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

36.9K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
36.9K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

212
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
212

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brain Transcriptomics Across Diverse Sleep-Wake Manipulations Reveals Multiple Homeostatic Pathways in <i>Drosophila</i>.

bioRxiv : the preprint server for biology·2026
Same author

The Negative Effects of Travel on Student Athletes Through Sleep and Circadian Disruption.

Journal of biological rhythms·2023
Same author

Temperature-driven coordination of circadian transcriptome regulation.

bioRxiv : the preprint server for biology·2023
Same author

Circadian programming of the ellipsoid body sleep homeostat in <i>Drosophila</i>.

eLife·2022
Same author

Glial immune-related pathways mediate effects of closed head traumatic brain injury on behavior and lethality in Drosophila.

PLoS biology·2022
Same author

The E3 ubiquitin ligase adaptor <i>Tango10</i> links the core circadian clock to neuropeptide and behavioral rhythms.

Proceedings of the National Academy of Sciences of the United States of America·2021
Same journal

Sleep, circadian, and mental health in neurodivergent neurotypes: Lived experience perspective on the research landscape and roadmaps.

Sleep·2026
Same journal

Nighttime light exposure is associated with metabolic dysfunction in schizophrenia: A cross-sectional analysis of the LENS study.

Sleep·2026
Same journal

Sleep Need Outcompetes Preparation: Reframing Sleep Initiation Through Naturalistic Behaviour.

Sleep·2026
Same journal

The Quest for Automated Pediatric Sleep Scoring: Are We There Yet?

Sleep·2026
Same journal

Sex Differences in the Sleep Architecture and Sleep-Disordered Breathing in C57BL/6 J Mice.

Sleep·2026
Same journal

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

Sleep·2026
See all related articles

Related Experiment Video

Updated: Aug 31, 2025

Assaying Locomotor Activity to Study Circadian Rhythms and Sleep Parameters in Drosophila
18:08

Assaying Locomotor Activity to Study Circadian Rhythms and Sleep Parameters in Drosophila

Published on: September 28, 2010

47.1K

SleepMat: a new behavioral analysis software program for sleep and circadian rhythms.

Shiju Sisobhan1, Clark Rosensweig1, Bridget C Lear1

  • 1Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.

Sleep
|August 23, 2022
PubMed
Summary
This summary is machine-generated.

A new software, SleepMat, offers user-friendly, high-throughput analysis of fruit fly sleep and circadian rhythms. This tool integrates with Drosophila genetics for comprehensive data insights.

Keywords:
DrosophilaDAM systembehavioral analysiscircadian rhythmsleep

More Related Videos

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

12.1K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

8.6K

Related Experiment Videos

Last Updated: Aug 31, 2025

Assaying Locomotor Activity to Study Circadian Rhythms and Sleep Parameters in Drosophila
18:08

Assaying Locomotor Activity to Study Circadian Rhythms and Sleep Parameters in Drosophila

Published on: September 28, 2010

47.1K
Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

12.1K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

8.6K

Area of Science:

  • * Chronobiology and behavioral neuroscience.

Background:

  • * Accurate analysis of sleep and circadian rhythms is crucial for understanding biological processes.
  • * Existing tools for analyzing Drosophila Activity Monitoring system data can be cumbersome.

Purpose of the Study:

  • * To introduce SleepMat, a novel, publicly available software for analyzing Drosophila Activity Monitoring system data.
  • * To provide a flexible and user-friendly platform for high-throughput sleep and circadian analysis.

Main Methods:

  • * Developed using the Matlab platform.
  • * Features an intuitive graphical user interface (GUI).
  • * Designed for flexible customization of data inputs.

Main Results:

  • * SleepMat quantifies numerous sleep and circadian parameters.
  • * Parameters include: period, actogram, anticipation, sleep amount, bout length, bout number, activity, sleep deprivation, latency, lifespan, and eduction.
  • * Enables high-throughput data analysis.

Conclusions:

  • * SleepMat facilitates accessible, high-throughput analysis of diverse sleep and circadian parameters.
  • * The software leverages the genetic strengths of Drosophila for advanced research.
  • * It empowers researchers with a powerful tool for chronobiology studies.