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Toxic epidermal necrolysis after first dose of Pfizer-BioNTech (BNT162b2) vaccination with pharmacogenomic testing
Nunthana Siripipattanamongkol1, Sirawich Rattanasak1, Chanya Taiyaitieng2
1Departments of Pediatrics, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
Abstract:
Toxic epidermal necrolysis (TEN) is a rare and acute life-threatening condition and one of the severe cutaneous adverse drug reactions. There are limited data on TEN from the COVID-19 vaccine regarding its pathogenesis, treatment, and prognosis, particularly in children. We report a case of COVID-19 vaccine-induced TEN and the patient's human leukocyte antigen pharmacogenomic profile.
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