Related Experiment Video
Updated: Aug 31, 2025

05:37
Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
Published on: April 4, 2025
823
Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA
1Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. liujw@uwaterloo.ca.
Abstract:
K+ enhanced the intrinsic fluorescence of a series of G-quadruplex DNAs, while Pb2+ quenched the fluorescence. The metals showed interesting quadruplex binding kinetics with various DNA sequences.

