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Updated: Aug 31, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Coronary revascularization after surgical aortic valve replacement
Mevlüt Çelik1, Andras P Durko1, Stuart J Head1,2
1Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
Insights
Coronary revascularization after surgical aortic valve replacement (SAVR) occurred in 6.9% of patients over 20 years. Previous revascularization significantly increased this risk, a finding relevant for transcatheter aortic valve replacement decisions.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- The necessity of coronary revascularization post-aortic valve intervention remains unclear.
- Data on revascularization rates after surgical aortic valve replacement (SAVR) are crucial for treatment and prosthesis selection.
- This study analyzes coronary revascularization incidence and characteristics following SAVR.
Purpose of the Study:
- To determine the incidence of coronary revascularization after SAVR.
- To identify predictors of coronary revascularization after SAVR.
- To characterize revascularization procedures performed after SAVR.
Main Methods:
- Analysis of 420 patients who underwent isolated SAVR between 1987 and 2015.
- Assessment of cumulative incidence using a competing risk approach.
- Identification of predictors for revascularization during follow-up.
Main Results:
- The 20-year cumulative incidence of coronary revascularization after SAVR was 6.9%.
- The linearized rate of revascularization was 6.2 per 1000 patient-years.
- Prior revascularization before SAVR was an independent predictor of subsequent revascularization (HR 6.6, P < .001).
Conclusions:
- Coronary revascularization is infrequent but occurs in 6.9% of patients up to 20 years post-SAVR.
- Patients with prior revascularization are at higher risk.
- Findings may inform decisions for transcatheter aortic valve replacement patients.
Objective:
It remains unclear how often coronary revascularization is necessary after aortic valve interventions, either by surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement. However, these data are relevant for treatment and prosthesis choice. The authors sought to analyze the incidence and characteristics of coronary revascularization after SAVR during follow-up.
Methods:
Of 2256 patients undergoing isolated SAVR between 1987 and 2015, 420 patients (mean age 56.9 ± 15.5 years, 66.9% male) were followed at the Erasmus Medical Center. Incidence, predictors, and characteristics of coronary revascularization were analyzed. Cumulative incidence of revascularization was assessed using a competing risk approach.
Results:
Mean follow-up after SAVR was 17.2 years (total of 4541 patient-years). A total of 24 patients underwent 28 procedures of revascularization. The cumulative incidence of revascularization after SAVR was 0.5%, 2.2%, 4.1%, and 6.9% at 1, 5, 10, and 20 years, respectively. The linearized rate of revascularization was 6.2 per 1000 patient-years. Percutaneous coronary intervention was the most common revascularization method (64%; N = 18/28). Revascularization before SAVR (N = 36/420; of whom 27 percutaneous coronary intervention) was an independent predictor of revascularization during follow-up (hazard ratio, 6.6; 95% confidence interval, 2.6-17.1; P < .001).
Conclusions:
After SAVR, the rate of coronary revascularization was 6.9% (N = 24/420) at 20-year follow-up. Patients were at particular risk if they had undergone previous revascularization before SAVR. These data may furthermore be relevant to the transcatheter aortic valve replacement population.
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