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Cost-Effective Fiber Optic Solutions for Biosensing.

Cátia Leitão1, Sónia O Pereira1, Carlos Marques1

  • 1i3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.

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|August 25, 2022
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Summary

Optical fiber biosensors (OFBs) offer a cost-effective, portable solution for real-time health and environmental monitoring. This review highlights various OFB configurations and smartphone-based interrogation methods for point-of-care applications.

Keywords:
POC monitoringcancer biomarkerscardiovascular biomarkersenvironmental monitoringoptical interrogation methodssmartphone optical biosensors

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Optoelectronics

Background:

  • Optical fiber sensors are versatile biosensing tools.
  • Optical fiber biosensors (OFBs) offer advantages like real-time monitoring, miniaturization, and portability for point-of-care (POC) testing.

Purpose of the Study:

  • To review cost-effective optical fiber biosensors (OFBs).
  • To discuss different fiber configurations and packaging techniques for medical applications.
  • To present smartphone-based interrogation methods for OFBs.

Main Methods:

  • Review of reported OFB configurations (end-face reflected, unclad, D- and U-shaped, tips, ball resonators, tapered, light-diffusing, specialty fibers).
  • Discussion of packaging techniques for medical implementation (subcutaneous, percutaneous, endoscopic, wearable).
  • Analysis of smartphone-based interrogation architectures and applications.

Main Results:

  • OFBs provide a reliable and versatile platform for biosensing.
  • Various fiber configurations and packaging methods enhance OFB applicability in medicine.
  • Smartphone integration enables cost-effective OFB interrogation.

Conclusions:

  • OFBs are highly promising for cost-effective, portable biosensing.
  • OFBs can be applied in critical areas such as cancer biomarker detection, cardiovascular monitoring, and environmental sensing.