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Updated: Jun 27, 2026

Fabrication and Testing of Microfluidic Optomechanical Oscillators
Published on: May 29, 2014
Biomechanical Sensing Using Gas Bubbles Oscillations in Liquids and Adjacent Technologies: Theory and Practical
Ivan S Maksymov1, Bui Quoc Huy Nguyen1, Sergey A Suslov2
1Optical Sciences Centre, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Gas bubbles in liquids can act as biosensors within the body, detecting mechanical signals. These bubble-based biosensors are detectable using ultrasound and photoacoustic imaging, offering new diagnostic possibilities.
Area of Science:
- Biomedical Engineering
- Acoustics
- Biosensing Technologies
Background:
- Gas bubbles are ubiquitous in liquids and biological systems.
- Bubbles can function as internal biomechanical sensors.
- These sensors are detectable via ultrasound and photoacoustic imaging.
Purpose of the Study:
- To review emergent sensing technologies utilizing acoustically driven bubble oscillations.
- To provide an accessible overview for a broad biosensing and transdisciplinary research community.
Main Methods:
- Review of acoustically driven bubble oscillation sensing technologies.
- Discussion of applications in biosensing within bodily fluids.
Main Results:
- Bubbles can be engineered or utilized as sensitive biomechanical sensors.
- Acoustic manipulation of bubbles enables signal generation for detection.
- Potential for non-invasive in-body sensing applications.
Conclusions:
- Acoustically driven bubbles represent a promising platform for novel biosensors.
- This technology has the potential for translation from theory to practical medical applications.
- Accessible review facilitates interdisciplinary research and development in biosensing.
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